翻訳と辞書
Words near each other
・ Protein fragment library
・ Protein function prediction
・ Protein G
・ Protein geranylgeranyltransferase type I
・ Protein geranylgeranyltransferase type II
・ Protein histidine kinase
・ Protein I-sites
・ Protein IB5
・ Protein Information Resource
・ Protein inhibitor of activated STAT
・ Protein inhibitor of activated STAT2
・ Protein isoform
・ Protein K
・ Protein K (gene expression)
・ Protein K (porin)
Protein kinase
・ Protein kinase A
・ Protein kinase B
・ Protein kinase C
・ Protein kinase C zeta type
・ Protein kinase D1
・ Protein kinase domain
・ Protein kinase inhibitor
・ Protein kinase N1
・ Protein kinase R
・ Protein kinase, AMP-activated, alpha 1
・ Protein L
・ Protein ligand
・ Protein Local Optimization Program
・ Protein losing enteropathy


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Protein kinase : ウィキペディア英語版
Protein kinase

A protein kinase is a kinase enzyme that modifies other proteins by chemically adding phosphate groups to them (phosphorylation). Phosphorylation usually results in a functional change of the target protein (substrate) by changing enzyme activity, cellular location, or association with other proteins. The human genome contains about 500 protein kinase genes and they constitute about 2% of all human genes. Up to 30% of all human proteins may be modified by kinase activity, and kinases are known to regulate the majority of cellular pathways, especially those involved in signal transduction. Protein kinases are also found in bacteria and plants.
==Chemical activity==

The chemical activity of a kinase involves transferring a phosphate group from a nucleoside triphosphate (usually ATP) and covalently attaching it to specific amino acids with a free hydroxyl group. Most kinases act on both serine and threonine (serine/threonine kinases), others act on tyrosine (tyrosine kinases), and a number act on all three (dual-specificity kinases). There are also protein kinases that phosphorylate other amino acids, including histidine kinases that phosphorylate histidine residues.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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